24 Postdoctoral Fellowship at Karolinska Institute, Sweden

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier. The candidate must hold a PhD equivalent to a Swedish doctoral degree in the field of immunology. The candidate must fully master multidimensional (>20 parameters) flow cytometry analysis and sorting, as well as be experienced in scRNAseq including analysis. Experience in isolation and in vitro culturing of primary immune cells is a requirement, as is basic functional in vitro assessments of immune cell function such as intracellular cytokine stainings, ELISA etc. The candidate should have a strong publication track-record. The candidate should be self-motivated, have good communications skills and a proven ability to interact effectively and work productively in an interdisciplinary team. Fluency in English is a requirement.

Mutations of mtDNA cause mitochondrial diseases and are heavily implicated in age-associated disease and the normal ageing process. The postdoc positions will be focused on studies of how inherited and somatic mtDNA mutations in mammals impair oxidative phosphorylation to cause organ dysfunction. Mechanisms for purifying selection of mutated mtDNA in the maternal germline will also be studied. The group of Nils-Göran Larsson focuses on understanding molecular processes determining how mitochondrial dysfunction causes disease and ageing by using biochemistry, molecular biology and modern -omics approaches. In addition, advanced mouse models, including conditional knockout strains and strains with mtDNA mutations generated by gene editing, will be an important component of the project.

We seek a curious, highly motivated, and creative postdoc with a strong background in stem cell biology. The ideal candidate should have experience working with mouse models and programming languages to analyze sequencing data. Experience with organoid cultures, molecular biology, next-generation sequencing, and large-scale bioinformatics analysis is a strength. Excellent interpersonal and communication skills (in English written and verbal) is required. Emphasis will be also placed on personal suitability, fitting well into the current research group.

We are looking for a postdoctoral researcher to work in Erik Benson new research group based at Scilifelab campus Solna, as a part of the larger group of prof Birgitta Henriques Normark. The group focuses on using DNA nanotechnology to develop libraries of DNA structures with large shape diversity. We use these structures to perform selection experiments combined with sequencing to find the structures with the best properties. The goal is to develop alternatives to antibodies that are fast to develop and produce, and are readable by sequencing. As a member of the group you become a part of the Scilifelab community and the unit for microbiology-bacteriology at the Karolinska Institute.

We seek a curious, highly motivated, and creative postdoc with a strong background in stem cell biology. The ideal candidate should have experience working with mouse models and programming languages to analyze sequencing data. Experience with mammalian cell cultures, molecular biology, next-generation sequencing, and large-scale bioinformatics analysis is a strength. Excellent interpersonal and communication skills (in English written and verbal) is required. Emphasis will be also placed on personal suitability, fitting well into the current research group.

We search for a postdoctoral scholar to work in the area of phage biology and bacterial defense systems with a focus on functional characterization of Mycobacterium tuberculosis/Mycobacterium abscessus systems to restrict phage replication. As a member of the Fossati lab, you will apply and develop novel genetic screenings (based on CRISPRi) to identify bacterial genes influencing phage replication and characterize them in their molecular context using interaction proteomics (affinity purification, proximity labelling, co-fractionation mass spectrometry).  As a Postdoctoral Researcher, you will assume a prominent role in project design and management, oversee data generation, conduct analyses, and provide insightful interpretations. Collaboration with fellow team members, other groups at KI/SciLifeLab will be a key aspect of your role. You will be responsible for disseminating scientific findings through the authorship of research papers, active participation in scientific conferences, and effective communication with colleagues.

The Department of Biosciences and Nutrition performs research and education in several areas of medical sciences including cancer biology, aging, molecular endocrinology, functional genomics, systems biology, structural biology, protein biochemistry, immunology, and nutrition. It offers an excellent international research and working environment, including around 200 scientists, students, administrative and technical personnel. The Department resides in Neo at Campus Flemingsberg, a biomedical research building, aimed at being a creative and open environment that enables meetings, synergies, and exploration of areas of mutual interest across disciplines

This postdoc project will be carried out in the research group of Assoc Prof Pauliina Damdimopoulou at the Division of Obstetrics and Gynecology (OBGY) of the Department of Clinical Science, Intervention and Technology. Research and education at OBGY are focused on the many aspects of women’s reproductive health including ovarian biology, endometrial receptivity, fertility preservation, reproductive toxicology, stem cell biology, developmental biology, and fetal medicine. The present project is a part of the newly funded European project MERLON where impacts of endocrine disruptive chemicals on reproductive health in women are studied.

This postdoc project will be carried out in the research group of Assoc Prof Pauliina Damdimopoulou at the Division of Obstetrics and Gynecology (OBGY) of the Department of Clinical Science, Intervention and Technology. Research and education at OBGY are focused on the many aspects of women’s reproductive health including ovarian biology, endometrial receptivity, fertility preservation, reproductive toxicology, stem cell biology, developmental biology, and fetal medicine. The present project is a part of the newly funded European project MERLON where impacts of endocrine disruptive chemicals on reproductive health in women are studied.

We seek a curious, highly motivated and creative postdoc with a strong background in molecular biology, placental biology and stem cell biology. The ideal candidate should have experience with programming languages to analyze sequencing data. The candidate should also have a good team spirit and bring a keen interest in solving intricate scientific questions. Experience with mammalian cell cultures, molecular biology, next-generation sequencing and large-scale bioinformatics analysis is a strength. Excellent interpersonal and communication skills (in English written and verbal) is required. Emphasis will be also placed on personal suitability, fitting well into the current research group.

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier. The postdoctoral candidate must have a background in computational biology, including sequencing-based projects and/or single-cell genomics. Meriting is experience in efficient computational strategies for processing large-scale data sets (Tb data; multi-core; Python; Rust) and explorative analyses of single-cell data (incl. biological filtering, separating biological and technical signals, multidimensional projections).

We are looking for a curiosity-driven, inquisitive and enthusiastic person interested in our area of research and ready to explore new avenues in science. The candidates should have a collaborative approach to research, work productively in a team, and contribute to a good social environment in the laboratory. The applicant shall hold a Ph.D. degree in natural or engineering sciences. The candidates with previous experience in biosensor design and microfabrication will be prioritized. The candidate should have documented experience with electrochemical biosensors. Experience in synthetic and semi-synthetic biorecognition design and polymer chemistry is significant merit. Experience with clean room facility and electron microscopy are not required but is considered merit. The applicant needs to have a high degree of independence and motivation but should have no problems working in a team, given the collaborative nature of the project. Fluency in English is a requirement. To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

The ideal candidate will be a Medical Doctor. We are looking for a highly motivated and dedicated individual who is passionate about full-time research and has the potential to work both independently and within a translational team. The daily work is performed at Bioclinicum, Karolinska University Hospital Solna, and requires full-time dedication. Experience in advanced statistical modeling (using R), biomechanical modeling (such as finite element analysis and/or computational fluid dynamics), and artificial intelligence-based methods is highly desirable. The appointed person will be expected to plan and carry out research projects independently and in conjunction with the team leaders, and to participate in national and international collaboration networks. Willingness to work flexibly to achieve project demands and targets as agreed upon within a team is necessary. Being able to organize and prioritize one’s own work, as well as organize research within the project timetable, is essential. Maintaining accurate and up-to-date records is also necessary. The applicant must have experience in teaching and tutoring since there will be some work-related supervising assignments included in the position, mostly of medical students. Fluency in English and Swedish is a requirement, as reading patient records, recruitment and follow-up of patients for clinical trials will be part of the role. Good social and analytical skills are essential. The ability to travel to other countries is also essential.

Applicants should hold a Ph.D. or equivalent expertise in bioinformatics. Coding skills in R or Python are important and will be assessed through a brief coding evaluation, along with your application of basic statistical tools, during the interview. Please submit your GitHub profile (if you have one with a track record of > 1 year) for additional assessment. Previous experience in plasma proteomics, metabolomics, and mass spectrometry is a plus. Interest in immunology is a prerequisite, and knowledge of this research field is an advantage.

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

The ideal candidate should have a medical background and hold a Doctoral (or be near completion) degree in medicine or pharmacy. The ideal candidate should also have demonstrated experience in the field of chronic kidney disease. Demonstrable advanced skills and expertise in R programming, STATA, or similar languages and ability to collaborate well within multi-disciplinary teams and independently are essential as well as experience in research on nephrology or nephrology training. Experience in propensity score/s, instrumental variable/s, and/or other methods to adjust for confounding for indication in pharmaco-epidemiological studies, experience in prediction modelling and good track record of peer reviewed scientific publications are desirable. The candidate needs good skills in English, both written and spoken.

The postdoctoral fellow will perform studies on spinal cord regeneration with special focus on establishment and re-organization of neural networks during regeneration. The tasks will involve comprehensive mapping of neural networks, cell tracking within the CNS as well as molecular profiling and manipulation of regeneration. The successful candidate will be part of a highly interactive multinational and multidisciplinary team covering expertise in molecular biology, cell biology, neuroscience, regeneration biology, mathematical modelling and robotics. Active participation in local group discussions and journal clubs will be expected, fostering a collaborative environment.

We are seeking an ambitious postdoctoral researcher with a PhD and background in molecular and/or systems neuroscience. Experience with wet-lab single-cell ‘omics protocols and bioinformatics skills are of advantage. Fluency in English, both written and spoken, is a requirement. To be eligible for employment as a postdoctoral researcher  a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

We seek a highly motivated postdoctoral fellow to join the team of associate professor Hanna Brauner in focusing on finding novel pathogenic mechanisms and biomarkers for patients with cutaneous lymphoma. We have access to unique clinical material, including fresh patient material from the Dermatology clinic where Hanna Brauner is specialist in dermatology and responsible for patients with cutaneous lymphoma, which we will assess in a truly translational approach, applying cutting edge methods to understand key clinical questions. The team of Hanna Brauner has a net-work of national and international collaborators among both basic science researcher and clinical researchers and is associated to the research group of professor Marie Wahren Herlenius. Our main research interest is cutaneous T cell lymphoma (CTCL), which is a rare and less studied type of lymphoma primarily engaging the skin. We recently published the first description of skin infiltration natural killer (NK) cells in patients with CTCL and found that they are increased in numbers and have an activity-impaired phenotype, partially driven by interactions with the tumor (Scheffschick et al, Front Immunol, 2023). The unique accessibility of CTCL allows for easy access to the tumor and the possibility to follow the development of the lymphoma and anti-lymphoma immune responses over time. Most of the patients with cutaneous T-cell lymphoma get an indolent disease, but for largely unknown reasons around 10-15% percent develop aggressive disease with high fatality. In these efforts our ultimate aims are to increase fundamental knowledge on the pathogenesis of cutaneous lymphoma and aid earlier identification of patients at risk of aggressive disease. We hope that findings from our studies will also be applicable for patients with other types of less accessible lymphoma subtypes.