13 Postdoctoral Fellowship at University of Leeds, West Yorkshire, England

Are you an ambitious researcher looking for your next challenge? Do you have a background in quantitative structural geology/geomechanics, and analysing brittle fractures and their patterns? Do you want to further your career in one of the UK’s leading research-intensive Universities, and develop fundamental research which will accelerate the Energy Transition?

The role is based in the Geosolutions Leeds research centre, an exciting new strategic investment by the University of Leeds as part of its Climate Plan, supporting the refocusing of research. Geosolutions Leeds brings together world-leading expertise in geology, engineering and social science to deliver an integrated systems approach to energy geoscience that will meet Net Zero goals.

Two research fellow positions are available in the laboratory of Professor Mark Harris, funded by a Wellcome Discovery Award.  We recently made the exciting discovery of a role for the kinase PKR and the down-stream transcription factor IRF1 in inducing expression of proteins that block virus assembly (DOI: 10.1371/journal.ppat.1010812), uncovering a hitherto unrecognised aspect of innate antiviral immunity.  These positions will focus on identifying and characterising these novel antiviral effectors, initially using hepatitis C virus as a model system, but also evaluating effects on other pathogenic viruses such as Chikungunya virus and SARS-CoV-2.  The project will initially involve transcriptomic analysis to identify genes regulated by PKR/IRF1, followed by investigation of their potential role in blocking assembly of infectious virus particles. The positions provide an opportunity to conduct ground-breaking research into the host response to virus infection and would suit individuals who have experience in working with pathogenic viruses in high containment, working with RNA and proven ability to generate and interpret ‘omics data.  The successful applicants will join a large, interdisciplinary laboratory shared between multiple investigators and working on a range of viruses.

We are seeking a Postdoctoral Research Fellow to join the Institute for Geophysics and Tectonics at the University of Leeds. This role is focused on the geodynamics of subduction, and related processes.  The Research Fellow will work with Dr Tim Craig and his research group, and will work on the development and application of numerical geodynamic models focused on aspects of the subduction process.  There may also be scope to include elements of observational seismology.  A number of subject areas are available for study, depending on the Fellows’ interests and skill: (a) processes controlling the seismicity within subducting slabs, (b) processes controlling the thermo-rheological evolution of subducting slabs, (c) processes controlling the occurrence of seismicity in the Outer Rise, and (d) processes controlling the interaction between earthquakes. 

Do you have a background in chemical science and engineering, and industrial research experience, with knowledge in the crystallography and particle technology aspects associated with the processing and performance of inorganic materials, then this position will interest you.

Polyhalite is an evaporite mineral, specifically a hydrated ternary sulfate of potassium, calcium and magnesium with formula: K2Ca2Mg(SO4)4·2H2O. It is an important commodity chemical feedstock, with particular utility as a low chloride containing fertiliser. The only polyhalite currently being mined in the world comes from below the North Yorkshire National Park which extends off the North Sea coast in the UK. Polyhalite is the first natural potassium bearing mineral to be utilised at scale, for crop production in 75 years.

We wish to recruit a Research Fellow to manage and work on a new project called Impact of an Intervention on Inequalities in Overprescribing – the 3i-o study. The project is funded by the National Institute for Health and Care Research through its Health and Social Care Delivery Research programme. The project aims to evaluate the impact, implementation and sustainability of audit and feedback on health inequalities in prescribing in general practice.

The Research Fellow will play a vital role in this research project aimed at understanding clinician and patient perspectives on optimising prescribing in general practice. The project seeks to explore beliefs regarding ethical, economic, and clinical challenges and benefits associated with reducing prescribing, particularly focusing on clinicians’ everyday practices and the specific needs of their practice populations. The Researcher, with support from the Work Package lead and another Research Fellow, will employ semi-structured interviews and ethnographic observations utilising the Listening Method to gather insights into clinician and patient perceptions and behaviours related to prescribing, patient demographics, available services, and contextual factors affecting prescribing decisions.

We are seeking a statistician/epidemiologist to lead a research programme investigating the molecular pathogenesis of vasculitis including treatment outcomes, with a focus on germline genetics.

The grand challenge of this workstream is to aim towards glucocorticoid-free treatment reducing long-term multimorbidity burden and treatment complications. This will be delivered through identifying new therapeutic targets, improving the accuracy and interpretation of diagnostics for giant cell arteritis, including predicting both those who will respond to glucocorticoid therapy and those who will suffer side effects.

The National Institute of Health Research Biomedical Research Centre (NIHR Leeds BRC) is a partnership between the Leeds Teaching Hospitals Trust (LTHT) the University of Leeds and the University of York. It is an international centre of excellence which exists to provide infrastructure to support translational research across: musculoskeletal disease (MSKD); cardiometabolic disease; surgical technologies; haematology; pathology; antimicrobial resistance. This post would work within the MSKD Vasculitis workstream, led by Professor Ann Morgan and Dr Mark Iles.

Are you experienced in computational modelling of complex flows for materials technology and ceramic coatings? Do you want to join a world class multidisciplinary team with industry partners? Are you looking for a new and exciting challenge to develop innovative digital tools combining CFD and machine learning to reduce manufacturing-induced deficiencies of ceramics?

We have a vacancy for an enthusiastic researcher with expertise in computational fluid dynamics (CFD), complex (non-Newtonian) flows, and machine learning knowledge to work with us in the Institute of Design, Robotics and Manufacturing (School of Mechanical Engineering, University of Leeds) and a local industry partner.

Are you an experienced and ambitious researcher looking for your next challenge? Are interested in pushing forward the state-of-the-art in innovative green vehicles and alternative fuels, and in assessing their environmental, social and economic sustainability? Do you want to further your career in one of the world leading research institutions in Transport?

Are you a creative process chemist looking for your next challenge? Does developing interdisciplinary solutions to poor air quality, a problem affecting the health of thousands of people, motivate you? Do you want to develop your networks both in one of the UK’s leading research-intensive institutions and with industrial partners?

You will join our team from the Schools of Chemistry, and Chemical and Process Engineering, working to develop LowCat, a new catalyst for NOx emissions mitigation. You will support a late-stage commercialisation project funded by the Science and Technology Facilities Council. The project builds on existing work demonstrating the effectiveness of LowCat for exhaust emissions mitigation and initial scale up of manufacture to the kg scale. The team at University of Leeds are working with partners from University College London, the ISIS Neutron facility and MinChem limited to deliver a scalable process for manufacture of an optimised catalyst to a range of target markets.

Are you passionate about stochastic analysis and its applications to differential equations? Do you have a PhD in Mathematics or a related discipline, and a strong background in stochastic analysis? Do you want to join a dynamic and collaborative research team?

We are looking for a Research Fellow to join our team working on stochastic analysis, with a focus on regularisation by noise phenomena. The post is funded by the EPSRC project EP/Y016955/1 “Regularisation by noise: beyond Itô’s theory” and aims to investigate the effects of noise on the well-posedness and qualitative properties of solutions to differential equations, with a focus on non-Markovian and/or infinite dimensional settings.

We are seeking a Research Fellow in Digital Flow Chemistry to develop automated reactor platforms for screening and optimising multistep reactions and apply these to synthetic case studies based on chemoenzymatic cascades.

The overarching project aims to develop an Industry 4.0 approach to integrated catalysis for sustainable synthesis. You will develop automated multistep reactor platforms using liquid handling robotics and continuous flow technology, to enable the combination of different types of catalysis into telescoped reaction sequences. This will require integration of machine learning algorithms and dynamic profiling techniques for reaction optimisation and mapping of the design space. You will work alongside other members of the group to apply these techniques on new catalytic cascades and pharmaceutical case studies.

Are you looking for a challenging and varied role which enables you to work across a diverse range of activities and with a variety of people? Are you an ambitious researcher looking for your next challenge with a good understanding of fashion and textiles including current challenges facing the sector? Are you a problem solver and a decision maker, able to contribute to a wide range of tasks both operational and strategic? Do you have excellent quantitative and qualitative research skills, with the ability to work effectively with a wide range of stakeholders and data sets?