12 Postdoctoral Fellowship at University of British Columbia, Canada

A postdoc fellowship position is available in Dr. Xuesen Dong’s lab (http://donglab.ca). Our research focuses on the mechanisms of therapy-resistant prostate cancers and the development of therapeutics to manage the disease (representative publications PMID: 32634132, 30910347, 27180064, 31819165). Ongoing projects include

1. deciphering cancer stem cell signal pathways to regulate neuroendocrine prostate cancers and
2. alternative RNA to regulate therapy-resistant prostate cancer progression.
3. drug development targeting Lin28 and TOP2

We are looking for multiple candidates to expand the existing projects to understand how Lin28 regulates stem cell networks to counteract therapy-induced stress and apply computer-aided drug design to develop Lin28 inhibitors. Candidates with animal handling, lentiviral manipulations, or ChIP-seq backgrounds are welcome. 

The Biosynthetic Enzymes Laboratory is an interdisciplinary research group working in the field of chemical biology with a focus on enzymes that construct natural products. We are seeking a Postdoctoral Fellow to our structural biology efforts. We study novel enzymes and use X-ray crystallography as a major tool to elucidate enzyme mechanisms. Recent work from our group has been published in Nature Chemistry, Nature Chemical Biology, PNAS, JACS, and Angewandte Chemie. We are seeking a postdoctoral fellow with broad interests in enzymology and in-depth training in the area of X-ray crystallography.

Our laboratory is located centrally in the vibrant UBC campus, with easy access to the ocean, mountains, and downtown. Vancouver is routinely ranked among the most livable cities in the world.

Fluid biomarkers can provide a detailed picture of neurological health and disease using relatively low-cost, accessible, objective, and scalable tools. There has been a rapid expanse of research into candidate blood-based biomarkers that show utility for the diagnosis and prognosis of neurological conditions. This position will focus on the statistical analysis for multiple projects involving large scale databases from various cohorts, including but not limited to traumatic or hypoxic brain injury, spinal cord injury, Alzheimer’s disease and related dementias, Multiple Sclerosis and healthy aging. The postdoctoral fellow will oversee their own individual project, to be developed in collaboration between the supervisor and a successful candidate. They will also provide guidance to lab members for other projects.

A postdoctoral research fellowship is available in the laboratory of Dr. Mari DeMarco in the Department of Pathology and Laboratory Medicine at the University of British Columbia (www.DeMarcoLab.ca). The fellow will lead the technological design, analytical validation and clinical evaluation of biofluid diagnostics to support early and accurate diagnosis neurodegenerative proteinopathies. The laboratory has a variety of analytical tools to pursue protein biomarker assay development, including an array of mass spectrometric and immunometric equipment. The intended primary methodology for this work will be quantitative/targeted protein mass spectrometry, and dependent on the fellow’s interests and goals, can be expanded to other analytical approaches. The primary focus of the lab is in advancing protein biomarkers/assays for neurodegenerative disorders such as Alzheimer’s disease, frontotemporal degeneration, Parkinson’s disease dementia. As the lab routinely engages with clinical partners to help solve urgent diagnostic challenges, the fellow may also have the opportunity to participate in building fit-for-purpose analytical tools for applications beyond dementia.   

The fellow will be based at St Paul’s Hospital, a teaching hospital of the University of British Columbia (UBC) located in downtown Vancouver, Canada. The DeMarco laboratory physically spans the domains and research and medicine with footprints in both the hospital laboratory and the UBC research centre at St. Paul’s Hospital. The candidate will work in a collaborative clinical research environment, and will interact regularly with physicians, laboratory medicine professionals, and other collaborators.

We have an outstanding opportunity for a Postdoctoral Research Associate at the Department of Radiology – University of British Columbia to engage in a closely collaborative research and development project with our industry partner, Torus Biomedical Solutions. The goal of this project is to develop a software solution that facilitates automatic image-based measurements within an existing intraoperative assessment product. The postdoctoral candidate will have the support, guidance, and supervision from the engineering team at the company led by Dr. Shahram Amiri as well as Dr. ilker Hacihaliloglu assistant professor at the Department of Radiology – University of British Columbia.

As a Postdoctoral Research Fellow, you’ll play a pivotal role in leading and contributing to the development of a machine learning approach to automate intraoperative X-ray-based measurements in orthopedic surgery. Your tasks will include establishing a pipeline for generating synthetic fluoroscopic images, conducting a thorough review of cutting-edge techniques, and designing and testing deep learning neural networks for bone segmentation and landmark annotation. You’ll also evaluate system performance in both simulated and real surgical environments. Working closely with a diverse team of engineers, researchers, and surgeons, your contributions can seamlessly integrate into an existing commercial product. Furthermore, your research findings will be submitted for publication in peer-reviewed journals.

The MéridaLabs research group is seeking a highly qualified postdoctoral fellow with specialization in Computational Fluid Dynamics (CFD) to join our dynamic team and support the research and development and design activities on low-emission hydrogen production technology. The ideal candidate will have 5+ years of academic or industrial experience in CFD simulation, thermo-fluid mechanics, heat transfer, kinetic modeling, and multi-phase flow simulation. Having expertise in high-temperature hydrocarbon pyrolysis, corrosive environments, and a deep understanding of hydrogen systems is a merit. The CFD PDF will work with the VulcanX R&D team to design a new generation of prototype reactors to enhance the hydrogen yield and improve their thermal efficiency.

The Wisnovsky & Williams labs (UBC Faculty of Pharmaceutical Sciences) are inviting applications for a jointly-supervised postdoctoral fellowship position. The fellow will lead a translational research program aimed at mapping and manipulating immune cell glycosylation in the tumor microenvironment. This research project will involve extensive work with syngeneic mouse models, primary human immune cells and clinical samples. The overall goal is to describe and functionally characterize glycosylated antigens on tumor-associated immune cells that can serve as next-generation targets and biomarkers for tumor immunotherapy.

This position is fully funded for the next five years by a CIHR Project Grant. A competitive salary (in the range of $55,000-$65,000+benefits, depending on experience level) will be offered to the successful candidate. Additional top-up compensation will also be provided to candidates who are able to attract external fellowship funding. The successful candidate will have extensive access to mentorship, professional development, networking and leadership opportunities to help support their career progression. The Williams & Wisnovsky labs are located in the state-of-the-art UBC Pharmaceutical Sciences Building, with full access to all required instrumentation and infrastructure. UBC is located just outside downtown Vancouver with easy access to both the mountains and the ocean.

We are looking for a postdoctoral fellow who will strive to make a meaningful impact on child health by contributing to leading-edge research aimed at improving pain management.

In light of the current opioid crisis, there is increased urgency to balance both safety and effectiveness of opioid-based analgesics, while simultaneously limiting the use of opioids. Given the resulting hesitancy associated with prescribing opioids, we are likely undertreating pain in children. This can be particularly devastating in children with high burdens of pain, such as children with cancer, where ongoing pain can interfere with brain development, disrupt behaviour, and increase the risk of chronic pain.

Safe and effective pain management is influenced by individual genetic differences that dictate both how we feel pain and how we respond to specific analgesics. Using pharmacogenomics, the study of how genetic variability contributes to individual drug responses, we are identifying genetic factors that can help predict an individual’s need for, and subsequent response to, opioids. 

As part of the Loucks Pain Management Pharmacogenomics (PMP) Lab, and the multi-disciplinary Canadian Pharmacogenomics Network for Drug Safety (CPNDS), the candidate will work closely with clinicians, scientists and patients across Canada to advance a pipeline from genetic discoveries to predictive genetic testing to help select the safest and most effective pain management strategies for children based on their unique genetic signatures. 

A postdoctoral fellow is being sought to join Chester Upham’s group of 10 collaborative and welcoming students and postdocs at UBC’s Vancouver campus. We are all working in some way to solve the CO2 problem by developing affordable new and out-of-the-box solutions. Several project options are available, including a new method of producing sustainable aviation fuels. 

As the lead researcher, you will have the freedom to develop a new catalyst, design a reactor, and/or synthesis and characterization your catalyst using all of our reactor systems and equipment. Your work will seek to understand and control the interaction between reactivity, catalyst surfaces, carbon and reactants. The majority of the work will be experimental and performed in the Department of Chemical and Biological Engineering’s 3 Heterogeneous Catalysis Labs and the Clean Energy Research Center under Dr. Upham’s supervision.

The candidate should have a PhD in Chemical Engineering, Chemistry, or a related field. Priority will be given to candidates with experimental experience in heterogeneous catalysis. The ideal candidate will work well with the other group members and collaborate on other projects.

Please email your CV with the names and contact information of three references along with your cover letter to chester.upham@ubc.ca. The annual salary for this position will be $55,000-$65,000, depending on your experience. Review of applications will begin immediately and this ad will remain posted until the position is filled; however, initial interviews are expect in early September. Please include use this job title as the title of your email.

Professor Simon Donner and the Climate and Coastal Ecosystem Lab at the University of British Columbia in Vancouver, Canada are searching for a postdoctoral researcher to participate in interdisciplinary research on ocean extreme events and their effects on coastal ecosystems. The research group conducts work at the intersection of climate and marine science, and informs policy and management at national and international scales.

Coastal ecosystems are at the frontlines of climate change. Marine heatwaves attributed to human-caused climate change have caused mass mortality and phase shifts in coral reefs, kelp forests and other coastal ecosystems. In addition to other areas of climate science and policy research, our group studies the drivers of marine heatwaves and their effects on coral reef and kelp systems at the global scale using large-scale numerical modelling and data analysis, as well as via field research in the equatorial Pacific in collaboration with local partners (e.g., Republic of Kiribati, Galápagos Archipelago).

The postdoc will have the option to focus on one or more project(s) related to i) assessing multiple drivers of coral bleaching using a global database developed in the group; ii) drivers and effects of warm-season marine heatwaves in the central equatorial Pacific, iii) projecting the effect of compound climate extremes (temperature, oxygen, etc.) on coral and kelp systems. The position comes with opportunities to engage in climate policy and adaptation discussions, and for training in climate communication and engagement.

At UBC, we believe that attracting and sustaining a diverse workforce is key to the successful pursuit of excellence in research, innovation, and learning for all faculty, staff and students. Our commitment to employment equity helps achieve inclusion and fairness, brings rich diversity to UBC as a workplace, and creates the necessary conditions for a rewarding career. 

The School of Biomedical Engineering (SBME) at the University of British Columbia (UBC), Vancouver campus invites applications for two full time Postdoctoral Research Fellow positions in the de Boer lab (https://deboer.bme.ubc.ca/). The initial appointment will be for one year with the possibility of extension subject to work performance and funding availability.

The Boer lab is a mixed computational/experimental group studying gene regulation using synthetic genomics and machine learning with the aim of having a sufficiently detailed understanding of gene expression that we can design personalized therapeutics to prevent and treat disease.

The Faculties of Medicine and Applied Science have partnered to create the SBME, a new flagship entity at UBC, and a top strategic priority for the University and both Faculties. The SBME is a nucleus for education and training, research, and innovation in biomedical engineering, creating new knowledge, new academic and training programs, and fostering translation and innovation. UBC SBME distinguishes itself by deep training in biology, and engineering science and design, enabling SBME researchers to address the most pressing biomedical challenges of the day. Our SBME faculty conduct research that advances our fundamental understanding of human biology, and yields technologies and therapies that advance our health and wellbeing.